As highlighted by the latest edition of the European Drug Report, Estonia is the country with the most drug-induced deaths per million population in Europe.
You will find more statistics at Statista
At 103 - 82 above the EU average - only Sweden comes close with 100 deaths. However, at the other end of the scale, as Statista's Martin Armstrong points out, Portugal, where drugs were decriminalised back in 2001, had only 6 per million people.
Looking outside of Europe, Estonia's problems are pulled into sharp relief by the rate in the United States. In 2016, there were a staggering 185 deaths per million.